Selank 10mg | NeuroPept Labs

Selank 10mg is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunomodulatory peptide tuftsin, studied extensively in anxiolytic, nootropic, and neuroimmune research. By appending a stabilizing Pro-Gly-Pro tripeptide to the tuftsin core, Selank demonstrates markedly greater metabolic stability than the native molecule, making it a widely used tool compound in preclinical models of stress, cognition, and GABAergic signalling.

NeuroPept Labs supplies Selank 10mg as a research-grade lyophilized peptide intended strictly for in vitro laboratory and analytical research use. All batches are synthesised under controlled conditions and verified through third-party analytical testing. COA validity can be confirmed at freedomdiagnosticstesting.com using the Accession Number, Client ID, or Search Code found in the product images.

Selank Mechanism of Action (Research Overview)

Selank is investigated as a multi-target regulatory peptide rather than a single-receptor ligand. Reported research mechanisms include:

• GABAergic modulation — alters expression of genes governing GABA-A receptor mediated neurotransmission, stabilising neuronal excitability under stress conditions
• BDNF regulation — rapidly elevates brain-derived neurotrophic factor (BDNF) expression in the hippocampus in rodent models of neuroplasticity
• Enkephalinase inhibition — slows enzymatic degradation of endogenous enkephalins, prolonging opioid-peptide signalling in stress-response research
• Monoamine and serotonergic balance — studied for effects on serotonin turnover and dopaminergic tone relevant to anxiety models
• Neuroimmune signalling — modulates interferon and cytokine expression, reflecting its tuftsin-derived immunoregulatory lineage

Research Applications

Current laboratory and preclinical investigation using the peptide spans multiple research domains:

• Anxiolytic research — benzodiazepine-comparable anxiolytic profiles without classical sedation or dependence markers in animal models
• Nootropic and cognition research — attention, memory consolidation, and executive-function endpoints via BDNF/neuroplasticity pathways
• Stress and behavioural neuroscience — chronic-mild-stress and elevated-plus-maze paradigms
• Neuroimmunology — cytokine and interferon-inducing activity linked to the tuftsin pharmacophore
• Combination peptide pharmacology — co-administration studies with GABAergic agents such as diazepam

Product Specifications

Storage and Handling

• Store lyophilized peptide at -20°C or below prior to reconstitution
• Avoid repeated freeze-thaw cycles to preserve structural integrity
• Protect from direct light, humidity, and room temperature exposure
• Reconstitute using sterile bacteriostatic water under aseptic conditions
• Once reconstituted, store at 4°C and use within recommended research timeframes

Frequently Asked Questions

What is Selank?

Selank is a synthetic heptapeptide analogue of the immunopeptide tuftsin, engineered with a Pro-Gly-Pro terminal extension for enhanced stability. It is studied as a regulatory peptide acting across GABAergic, BDNF, and enkephalinergic pathways in anxiolytic and nootropic research.

How does Selank differ from tuftsin?

It retains the Thr-Lys-Pro-Arg tuftsin core responsible for its immunomodulatory activity but adds a stabilising Pro-Gly-Pro sequence that dramatically increases resistance to enzymatic degradation, giving it a longer functional window in research models.

Is Selank studied alongside Semax?

Yes. The two peptides are both regulatory heptapeptides frequently examined together in nootropic and neuroprotective research because they act through complementary neuromodulatory and neurotrophic pathways.

What purity is NeuroPept Labs’ Selank 10mg?

Our Selank 10mg research peptide is supplied at 98% purity, verified by HPLC and third-party analytical testing. Full COA documentation is available for every batch and can be verified at freedomdiagnosticstesting.com.

Scientific References

1. Selank Enhances the Effect of Diazepam in Reducing Anxiety | PMC 2017
2. Peptides as Therapeutic Agents: Challenges and Opportunities | PMC/NIH 2023

Research Use Disclaimer: All products sold by NeuroPept Labs are intended strictly for in vitro laboratory research and scientific investigation by qualified professionals. They are not approved for human consumption, medical treatment, or veterinary use. Purchasers are responsible for compliance with applicable regulations in their jurisdiction.