Mitochondrial-derived peptides have become an area of growing interest in modern biological research. Among these compounds, MOTS-c has attracted significant attention due to its role in cellular metabolism, mitochondrial signaling, and stress-response pathways.
MOTS-c supplied by NeuroPept Labs is a synthetic, research-grade peptide provided in lyophilized form and intended exclusively for laboratory and scientific research applications.
What Is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino-acid peptide encoded by the mitochondrial genome. Unlike many peptides encoded in nuclear DNA, MOTS-c originates from mitochondrial DNA, making it a unique subject of study in mitochondrial biology and metabolic research.
Scientific literature has explored MOTS-c in experimental models related to:
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Cellular energy regulation
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Mitochondrial signaling pathways
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Metabolic stress adaptation
- AMPK-related molecular mechanisms
Research Focus Areas
In scientific literature, MOTS-c has been investigated in preclinical and experimental research settings that examine:
Mitochondrial Function
Studies explore how MOTS-c interacts with mitochondrial signaling pathways involved in cellular energy balance and adaptation mechanisms.
Metabolic Regulation Models
Research has examined MOTS-c within frameworks related to glucose utilization, metabolic stress, and energy homeostasis in laboratory models.
Cellular Stress Response
MOTS-c is frequently studied for its role in adaptive cellular responses under metabolic or oxidative stress conditions.
⚠️ These areas reflect research focus only and do not imply approved medical or therapeutic use.
Quality, Testing, and Handling
NeuroPept Labs supplies MOTS-c 10mg under strict quality standards. Each batch undergoes identity and purity verification through analytical testing methods such as HPLC and mass spectrometry.
Key characteristics:
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Research-grade synthetic peptide
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High purity (≥98%)
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Lyophilized for enhanced stability
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Certificate of Analysis (COA) available
For laboratory preparation, dilution of lyophilized peptides should be performed using appropriate laboratory-grade solutions under controlled research conditions.
Scientific References
The following peer-reviewed publications highlight experimental research involving MOTS-c:
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Lee, C. et al. (2015). Mitochondrial-derived peptides: A new perspective on aging. Journal of Gerontology Series A, 70(9), 1062–1073.
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Yoshioka, K. et al. (2018). The mitochondrial peptide MOTS-c enhances metabolic health in obesity-induced insulin resistance. Nature Communications, 9, 4516.
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Huang, H. et al. (2020). MOTS-c promotes muscle regeneration through training-induced mitochondrial adaptation. Cell Reports, 32(11), 108155.
These references are provided for informational and research context only.
Conclusion
MOTS-c 10mg represents a synthetic, research-grade peptide designed to support laboratory studies focused on mitochondrial biology, metabolic signaling, and cellular stress mechanisms. By providing verified, high-purity peptide materials, NeuroPept Labs supports advanced scientific research in controlled laboratory environments.
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